Dr. Marie-Claude Potier is Director of Research at the French National Center for Scientific Research (CNRS) and Co-Group Leader of the “Alzheimer’s and Prion Diseases” research group at ICM-Institut du Cerveau et de la Moelle Epinière (Brain and Spine Institute), at the Pitié-Salpêtrière Hospital, Paris, France.
Dr. Marie-Claude Potier and her team investigate the role of lipids, particularly cholesterol and alipoprotein E in the secretion and neuronal transport, their involvement in endosomal modifications that occur early during the course of the disease and novel mechanisms of AB toxicity identified in vivo. She initiated translational research programs with on-site clinicians and developed a microfluidic platform for studying the transcription of single cells and producing microfluidic devices for neuronal cultures.
After a PharmD in Neuropharmacology at the University Réné Descartes, Paris, France and a PhD at the University Pierre and Marie Curie, Paris, France, she was trained in molecular and cellular biology during three years post-doct at the MRC Laboratory of Molecular Biology, Cambridge, UK. She returned to the Alfred Fessard Institute when she obtained a permanent scientific staff position at CNRS and later joined the School of Physic & Chemistry (ESPCI), Paris France. She lately joined the ICM in 2008.
Dr. Marie-Claude Potier has been working for the past twenty-five years on Down syndrome (DS) and is now developing pharmacological treatments for increasing cognition in DS.
Dr. Marie-Claude Potier published more than one hundred papers in scientific journals and is since 2017 Corresponding Member of the French Academy of Medicine. She received the Dagnan-Bouveret Prize from The French Science Academy in 2005.